I respectfully disagree. Players should be able to pick up the game and "just play". From that angle, the controls are the most important part of the game. Think of it like the opening page of a book. Players will judge the game based on how fast they can learn the controls. Intuitive and minimal configuration is key for that first impression.
This probably means that the controls are crap for advanced players--that's OK from a retention angle. Advanced players usually desire the kind of precise control that drives newbies crazy... so it's not such a bad thing to have them run through a menus to customize their experience.
Yeah I'm kind of being harsh . Controls should be playable at the start of the game and they're pretty counter-intuitive right now.
Maybe a small short video on the side in the very beginning with a picture of a keyboard showing where the buttons are would help.
If anyone is interested I mapped the four abilities to Q, W, A, and S, I made aim up/down to E/D and I made interact R. I find it works well.